![]() ![]() “Disease-causing mutations were found in nearly a quarter of the patients we studied,” said Sander Markx, MD, the Director of the Center for Precision Neuropsychiatry at Columbia University Medical Center, who conducted a preliminary genetic study of 50 patients who all spent many years hospitalized with severe forms of mental illness. New evidence suggests that individuals with more severe forms of mental illness may have more clearly identifiable and robust genetic risk factors than those with milder illnesses. We hope that this unique study will transform our understanding of some fundamental brain mechanisms, and open up entirely new treatment avenues.” Anna Chapman, MD, the President of the Chapman Perelman Foundation, noted that “in recent years, advances in precision medicine has led to breakthroughs in the understanding and treatment of cancers and other conditions, while similar progress in the domain of neuropsychiatry has lagged. ![]() With this highly innovative study, the Columbia research team will be able to pave the way for a paradigm shift in the field of psychiatry by ultimately introducing a precision medicine-based approach to the diagnostics and treatment of severe psychiatric diseases. Kolb Professor of Psychiatry and Chair of the Department of Psychiatry at CUIMC. “This generous gift from the Chapman Perelman Foundation provides an important opportunity to apply cutting edge science in an attempt to rescue people with refractory mental conditions,” said Jeffrey Lieberman, MD, the Lawrence C. This groundbreaking research project will enable the IGM and the Department of Psychiatry at Columbia to explore the underlying genetic and molecular causes of these particularly devastating forms of mental illness. This gift will be used to pilot a 2-year study to identify different genotypes in up to 200 patients with chronic and severe forms schizophrenia and related psychotic disorders. New York, NY (February 20, 2018)-The Chapman Perelman Foundation will contribute $500,000 to Columbia University Irving Medical Center’s (CUIMC) Institute of Genomic Medicine (IGM) and the Department of Psychiatry to investigate the genetic causes of mental illness. ![]()
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